Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition.
Identifieur interne : 000536 ( Main/Exploration ); précédent : 000535; suivant : 000537Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition.
Auteurs : P N A. Harris [Australie] ; J F Mcnamara [Australie] ; D C Lye [Singapour] ; J S Davis [Australie] ; L. Bernard [France] ; A C Cheng [Australie] ; Y. Doi [États-Unis] ; V G Fowler [États-Unis] ; K S Kaye [États-Unis] ; L. Leibovici [Israël] ; J. Lipman [Afrique du Sud] ; M J Llewelyn [Royaume-Uni] ; S. Munoz-Price [États-Unis] ; M. Paul [Israël] ; A Y Peleg [Australie] ; J. Rodríguez-Ba O [Espagne] ; B A Rogers [Australie] ; H. Seifert [Allemagne] ; V. Thamlikitkul [Thaïlande] ; G. Thwaites [Royaume-Uni] ; S Y C. Tong [Australie] ; J. Turnidge [Australie] ; R. Utili [Italie] ; S A R. Webb [Australie] ; D L Paterson [Australie]Source :
- Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [ 1469-0691 ] ; 2017.
Abstract
To define standardized endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infections (BSI).
DOI: 10.1016/j.cmi.2016.10.023
PubMed: 27810466
Affiliations:
- Afrique du Sud, Allemagne, Australie, Espagne, France, Israël, Italie, Royaume-Uni, Singapour, Thaïlande, États-Unis
- Angleterre, Caroline du Nord, Centre-Val de Loire, Michigan, Oxfordshire, Pennsylvanie, Région Centre, Wisconsin
- Oxford, Tours
- Université d'Oxford
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Electronic address: p.harris@uq.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author><author><name sortKey="Mcnamara, J F" sort="Mcnamara, J F" uniqKey="Mcnamara J" first="J F" last="Mcnamara">J F Mcnamara</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author><author><name sortKey="Lye, D C" sort="Lye, D C" uniqKey="Lye D" first="D C" last="Lye">D C Lye</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital and Yong Loo Lin School of Medicine, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital and Yong Loo Lin School of Medicine</wicri:regionArea><wicri:noRegion>Tan Tock Seng Hospital and Yong Loo Lin School of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Davis, J S" sort="Davis, J S" uniqKey="Davis J" first="J S" last="Davis">J S Davis</name><affiliation wicri:level="1"><nlm:affiliation>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia; Department of Infectious Diseases, John Hunter Hospital, Newcastle, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia; Department of Infectious Diseases, John Hunter Hospital, Newcastle, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Bernard, L" sort="Bernard, L" uniqKey="Bernard L" first="L" last="Bernard">L. Bernard</name><affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Unit, Tours University Hospital, Tours, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Infectious Diseases Unit, Tours University Hospital, Tours</wicri:regionArea><placeName><region type="region">Centre-Val de Loire</region><region type="old region">Région Centre</region><settlement type="city">Tours</settlement></placeName></affiliation></author><author><name sortKey="Cheng, A C" sort="Cheng, A C" uniqKey="Cheng A" first="A C" last="Cheng">A C Cheng</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic., Australia; Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic., Australia; Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Doi, Y" sort="Doi, Y" uniqKey="Doi Y" first="Y" last="Doi">Y. Doi</name><affiliation wicri:level="2"><nlm:affiliation>Division of Infectious Diseases, University of Pittsburgh School of Medicine, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Infectious Diseases, University of Pittsburgh School of Medicine, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Fowler, V G" sort="Fowler, V G" uniqKey="Fowler V" first="V G" last="Fowler">V G Fowler</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, NC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Duke University Medical Center and Duke Clinical Research Institute, Durham, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Kaye, K S" sort="Kaye, K S" uniqKey="Kaye K" first="K S" last="Kaye">K S Kaye</name><affiliation wicri:level="2"><nlm:affiliation>Wayne State University School of Medicine, Detroit Medical Center, Detroit, MI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Wayne State University School of Medicine, Detroit Medical Center, Detroit, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Leibovici, L" sort="Leibovici, L" uniqKey="Leibovici L" first="L" last="Leibovici">L. Leibovici</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine E, Beilinson Hospital, Rabin Medical Center, Petah-Tiqva, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Medicine E, Beilinson Hospital, Rabin Medical Center, Petah-Tiqva, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv</wicri:regionArea><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Lipman, J" sort="Lipman, J" uniqKey="Lipman J" first="J" last="Lipman">J. Lipman</name><affiliation wicri:level="1"><nlm:affiliation>Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, Qld, Australia; Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Qld, Australia; The University of Witwatersrand, Johannesburg, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, Qld, Australia; Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Qld, Australia; The University of Witwatersrand, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Llewelyn, M J" sort="Llewelyn, M J" uniqKey="Llewelyn M" first="M J" last="Llewelyn">M J Llewelyn</name><affiliation wicri:level="1"><nlm:affiliation>Division of Medicine, Brighton and Sussex Medical School, Brighton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, Brighton and Sussex Medical School, Brighton</wicri:regionArea><wicri:noRegion>Brighton</wicri:noRegion></affiliation></author><author><name sortKey="Munoz Price, S" sort="Munoz Price, S" uniqKey="Munoz Price S" first="S" last="Munoz-Price">S. Munoz-Price</name><affiliation wicri:level="2"><nlm:affiliation>Froedtert & Medical College of Wisconsin, Milwaukee, WI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Froedtert & Medical College of Wisconsin, Milwaukee, WI</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Paul, M" sort="Paul, M" uniqKey="Paul M" first="M" last="Paul">M. Paul</name><affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Rambam Health Care Campus and The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Division of Infectious Diseases, Rambam Health Care Campus and The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa</wicri:regionArea><wicri:noRegion>Haifa</wicri:noRegion></affiliation></author><author><name sortKey="Peleg, A Y" sort="Peleg, A Y" uniqKey="Peleg A" first="A Y" last="Peleg">A Y Peleg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Monash University, Melbourne, Vic., Australia; School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Microbiology, Monash University, Melbourne, Vic., Australia; School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Rodriguez Ba O, J" sort="Rodriguez Ba O, J" uniqKey="Rodriguez Ba O J" first="J" last="Rodríguez-Ba O">J. Rodríguez-Ba O</name><affiliation wicri:level="1"><nlm:affiliation>Unidad Clínica Intercentros de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospitales Universitarios Virgen Macarena y Virgen del Rocío-IBiS and Departamento de Medicina, Universidad de Sevilla, Seville, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unidad Clínica Intercentros de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospitales Universitarios Virgen Macarena y Virgen del Rocío-IBiS and Departamento de Medicina, Universidad de Sevilla, Seville</wicri:regionArea><wicri:noRegion>Seville</wicri:noRegion></affiliation></author><author><name sortKey="Rogers, B A" sort="Rogers, B A" uniqKey="Rogers B" first="B A" last="Rogers">B A Rogers</name><affiliation wicri:level="1"><nlm:affiliation>School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Seifert, H" sort="Seifert, H" uniqKey="Seifert H" first="H" last="Seifert">H. Seifert</name><affiliation wicri:level="1"><nlm:affiliation>German Centre for Infection Research (DZIF), Braunschweig, Germany; Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Centre for Infection Research (DZIF), Braunschweig, Germany; Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Thamlikitkul, V" sort="Thamlikitkul, V" uniqKey="Thamlikitkul V" first="V" last="Thamlikitkul">V. Thamlikitkul</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Thwaites, G" sort="Thwaites, G" uniqKey="Thwaites G" first="G" last="Thwaites">G. Thwaites</name><affiliation wicri:level="4"><nlm:affiliation>Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam; Nuffield Department of Medicine, University of Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam; Nuffield Department of Medicine, University of Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Tong, S Y C" sort="Tong, S Y C" uniqKey="Tong S" first="S Y C" last="Tong">S Y C. Tong</name><affiliation wicri:level="1"><nlm:affiliation>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT</wicri:regionArea><wicri:noRegion>NT</wicri:noRegion></affiliation></author><author><name sortKey="Turnidge, J" sort="Turnidge, J" uniqKey="Turnidge J" first="J" last="Turnidge">J. Turnidge</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Paediatrics and Molecular Biosciences, University of Adelaide, SA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Pathology, Paediatrics and Molecular Biosciences, University of Adelaide, SA</wicri:regionArea><wicri:noRegion>SA</wicri:noRegion></affiliation></author><author><name sortKey="Utili, R" sort="Utili, R" uniqKey="Utili R" first="R" last="Utili">R. Utili</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Second University of Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Internal Medicine, Second University of Naples</wicri:regionArea><wicri:noRegion>Second University of Naples</wicri:noRegion></affiliation></author><author><name sortKey="Webb, S A R" sort="Webb, S A R" uniqKey="Webb S" first="S A R" last="Webb">S A R. Webb</name><affiliation wicri:level="1"><nlm:affiliation>Royal Perth Hospital, and School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Royal Perth Hospital, and School of Medicine and Pharmacology, University of Western Australia, Perth, WA</wicri:regionArea><wicri:noRegion>WA</wicri:noRegion></affiliation></author><author><name sortKey="Paterson, D L" sort="Paterson, D L" uniqKey="Paterson D" first="D L" last="Paterson">D L Paterson</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Wesley Medical Research, Wesley Hospital, Toowong, Qld, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Wesley Medical Research, Wesley Hospital, Toowong, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27810466</idno><idno type="pmid">27810466</idno><idno type="doi">10.1016/j.cmi.2016.10.023</idno><idno type="wicri:Area/PubMed/Corpus">000756</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000756</idno><idno type="wicri:Area/PubMed/Curation">000753</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000753</idno><idno type="wicri:Area/PubMed/Checkpoint">000753</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000753</idno><idno type="wicri:Area/Ncbi/Merge">003E19</idno><idno type="wicri:Area/Ncbi/Curation">003E19</idno><idno type="wicri:Area/Ncbi/Checkpoint">003E19</idno><idno type="wicri:Area/Main/Merge">000531</idno><idno type="wicri:Area/Main/Curation">000536</idno><idno type="wicri:Area/Main/Exploration">000536</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition.</title><author><name sortKey="Harris, P N A" sort="Harris, P N A" uniqKey="Harris P" first="P N A" last="Harris">P N A. Harris</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld, Australia. Electronic address: p.harris@uq.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author><author><name sortKey="Mcnamara, J F" sort="Mcnamara, J F" uniqKey="Mcnamara J" first="J F" last="Mcnamara">J F Mcnamara</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Department of Microbiology, Pathology Queensland, Central Laboratory, Royal Brisbane & Women's Hospital, Brisbane, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author><author><name sortKey="Lye, D C" sort="Lye, D C" uniqKey="Lye D" first="D C" last="Lye">D C Lye</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital and Yong Loo Lin School of Medicine, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital and Yong Loo Lin School of Medicine</wicri:regionArea><wicri:noRegion>Tan Tock Seng Hospital and Yong Loo Lin School of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Davis, J S" sort="Davis, J S" uniqKey="Davis J" first="J S" last="Davis">J S Davis</name><affiliation wicri:level="1"><nlm:affiliation>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia; Department of Infectious Diseases, John Hunter Hospital, Newcastle, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia; Department of Infectious Diseases, John Hunter Hospital, Newcastle, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Bernard, L" sort="Bernard, L" uniqKey="Bernard L" first="L" last="Bernard">L. Bernard</name><affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Unit, Tours University Hospital, Tours, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Infectious Diseases Unit, Tours University Hospital, Tours</wicri:regionArea><placeName><region type="region">Centre-Val de Loire</region><region type="old region">Région Centre</region><settlement type="city">Tours</settlement></placeName></affiliation></author><author><name sortKey="Cheng, A C" sort="Cheng, A C" uniqKey="Cheng A" first="A C" last="Cheng">A C Cheng</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic., Australia; Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic., Australia; Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Doi, Y" sort="Doi, Y" uniqKey="Doi Y" first="Y" last="Doi">Y. Doi</name><affiliation wicri:level="2"><nlm:affiliation>Division of Infectious Diseases, University of Pittsburgh School of Medicine, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Infectious Diseases, University of Pittsburgh School of Medicine, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Fowler, V G" sort="Fowler, V G" uniqKey="Fowler V" first="V G" last="Fowler">V G Fowler</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, NC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Duke University Medical Center and Duke Clinical Research Institute, Durham, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Kaye, K S" sort="Kaye, K S" uniqKey="Kaye K" first="K S" last="Kaye">K S Kaye</name><affiliation wicri:level="2"><nlm:affiliation>Wayne State University School of Medicine, Detroit Medical Center, Detroit, MI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Wayne State University School of Medicine, Detroit Medical Center, Detroit, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Leibovici, L" sort="Leibovici, L" uniqKey="Leibovici L" first="L" last="Leibovici">L. Leibovici</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine E, Beilinson Hospital, Rabin Medical Center, Petah-Tiqva, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Medicine E, Beilinson Hospital, Rabin Medical Center, Petah-Tiqva, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv</wicri:regionArea><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Lipman, J" sort="Lipman, J" uniqKey="Lipman J" first="J" last="Lipman">J. Lipman</name><affiliation wicri:level="1"><nlm:affiliation>Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, Qld, Australia; Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Qld, Australia; The University of Witwatersrand, Johannesburg, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, Qld, Australia; Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Qld, Australia; The University of Witwatersrand, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Llewelyn, M J" sort="Llewelyn, M J" uniqKey="Llewelyn M" first="M J" last="Llewelyn">M J Llewelyn</name><affiliation wicri:level="1"><nlm:affiliation>Division of Medicine, Brighton and Sussex Medical School, Brighton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, Brighton and Sussex Medical School, Brighton</wicri:regionArea><wicri:noRegion>Brighton</wicri:noRegion></affiliation></author><author><name sortKey="Munoz Price, S" sort="Munoz Price, S" uniqKey="Munoz Price S" first="S" last="Munoz-Price">S. Munoz-Price</name><affiliation wicri:level="2"><nlm:affiliation>Froedtert & Medical College of Wisconsin, Milwaukee, WI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Froedtert & Medical College of Wisconsin, Milwaukee, WI</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Paul, M" sort="Paul, M" uniqKey="Paul M" first="M" last="Paul">M. Paul</name><affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Rambam Health Care Campus and The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Division of Infectious Diseases, Rambam Health Care Campus and The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa</wicri:regionArea><wicri:noRegion>Haifa</wicri:noRegion></affiliation></author><author><name sortKey="Peleg, A Y" sort="Peleg, A Y" uniqKey="Peleg A" first="A Y" last="Peleg">A Y Peleg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Monash University, Melbourne, Vic., Australia; School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Microbiology, Monash University, Melbourne, Vic., Australia; School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Rodriguez Ba O, J" sort="Rodriguez Ba O, J" uniqKey="Rodriguez Ba O J" first="J" last="Rodríguez-Ba O">J. Rodríguez-Ba O</name><affiliation wicri:level="1"><nlm:affiliation>Unidad Clínica Intercentros de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospitales Universitarios Virgen Macarena y Virgen del Rocío-IBiS and Departamento de Medicina, Universidad de Sevilla, Seville, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unidad Clínica Intercentros de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospitales Universitarios Virgen Macarena y Virgen del Rocío-IBiS and Departamento de Medicina, Universidad de Sevilla, Seville</wicri:regionArea><wicri:noRegion>Seville</wicri:noRegion></affiliation></author><author><name sortKey="Rogers, B A" sort="Rogers, B A" uniqKey="Rogers B" first="B A" last="Rogers">B A Rogers</name><affiliation wicri:level="1"><nlm:affiliation>School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic., Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Clinical Sciences, Monash Medical Centre, Monash University, and Monash Infectious Diseases, Monash Health, Clayton, Vic.</wicri:regionArea><wicri:noRegion>Vic.</wicri:noRegion></affiliation></author><author><name sortKey="Seifert, H" sort="Seifert, H" uniqKey="Seifert H" first="H" last="Seifert">H. Seifert</name><affiliation wicri:level="1"><nlm:affiliation>German Centre for Infection Research (DZIF), Braunschweig, Germany; Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Centre for Infection Research (DZIF), Braunschweig, Germany; Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Thamlikitkul, V" sort="Thamlikitkul, V" uniqKey="Thamlikitkul V" first="V" last="Thamlikitkul">V. Thamlikitkul</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Thwaites, G" sort="Thwaites, G" uniqKey="Thwaites G" first="G" last="Thwaites">G. Thwaites</name><affiliation wicri:level="4"><nlm:affiliation>Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam; Nuffield Department of Medicine, University of Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam; Nuffield Department of Medicine, University of Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Tong, S Y C" sort="Tong, S Y C" uniqKey="Tong S" first="S Y C" last="Tong">S Y C. Tong</name><affiliation wicri:level="1"><nlm:affiliation>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT</wicri:regionArea><wicri:noRegion>NT</wicri:noRegion></affiliation></author><author><name sortKey="Turnidge, J" sort="Turnidge, J" uniqKey="Turnidge J" first="J" last="Turnidge">J. Turnidge</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Paediatrics and Molecular Biosciences, University of Adelaide, SA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Pathology, Paediatrics and Molecular Biosciences, University of Adelaide, SA</wicri:regionArea><wicri:noRegion>SA</wicri:noRegion></affiliation></author><author><name sortKey="Utili, R" sort="Utili, R" uniqKey="Utili R" first="R" last="Utili">R. Utili</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine, Second University of Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Internal Medicine, Second University of Naples</wicri:regionArea><wicri:noRegion>Second University of Naples</wicri:noRegion></affiliation></author><author><name sortKey="Webb, S A R" sort="Webb, S A R" uniqKey="Webb S" first="S A R" last="Webb">S A R. Webb</name><affiliation wicri:level="1"><nlm:affiliation>Royal Perth Hospital, and School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Royal Perth Hospital, and School of Medicine and Pharmacology, University of Western Australia, Perth, WA</wicri:regionArea><wicri:noRegion>WA</wicri:noRegion></affiliation></author><author><name sortKey="Paterson, D L" sort="Paterson, D L" uniqKey="Paterson D" first="D L" last="Paterson">D L Paterson</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Wesley Medical Research, Wesley Hospital, Toowong, Qld, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, UQ Centre for Clinical Research, Brisbane, Qld, Australia; Wesley Medical Research, Wesley Hospital, Toowong, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author></analytic><series><title level="j">Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases</title><idno type="eISSN">1469-0691</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To define standardized endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infections (BSI).</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li><li>Allemagne</li><li>Australie</li><li>Espagne</li><li>France</li><li>Israël</li><li>Italie</li><li>Royaume-Uni</li><li>Singapour</li><li>Thaïlande</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Caroline du Nord</li><li>Centre-Val de Loire</li><li>Michigan</li><li>Oxfordshire</li><li>Pennsylvanie</li><li>Région Centre</li><li>Wisconsin</li></region><settlement><li>Oxford</li><li>Tours</li></settlement><orgName><li>Université d'Oxford</li></orgName></list><tree><country name="Australie"><noRegion><name sortKey="Harris, P N A" sort="Harris, P N A" uniqKey="Harris P" first="P N A" last="Harris">P N A. Harris</name></noRegion><name sortKey="Cheng, A C" sort="Cheng, A C" uniqKey="Cheng A" first="A C" last="Cheng">A C Cheng</name><name sortKey="Davis, J S" sort="Davis, J S" uniqKey="Davis J" first="J S" last="Davis">J S Davis</name><name sortKey="Mcnamara, J F" sort="Mcnamara, J F" uniqKey="Mcnamara J" first="J F" last="Mcnamara">J F Mcnamara</name><name sortKey="Paterson, D L" sort="Paterson, D L" uniqKey="Paterson D" first="D L" last="Paterson">D L Paterson</name><name sortKey="Peleg, A Y" sort="Peleg, A Y" uniqKey="Peleg A" first="A Y" last="Peleg">A Y Peleg</name><name sortKey="Rogers, B A" sort="Rogers, B A" uniqKey="Rogers B" first="B A" last="Rogers">B A Rogers</name><name sortKey="Tong, S Y C" sort="Tong, S Y C" uniqKey="Tong S" first="S Y C" last="Tong">S Y C. Tong</name><name sortKey="Turnidge, J" sort="Turnidge, J" uniqKey="Turnidge J" first="J" last="Turnidge">J. Turnidge</name><name sortKey="Webb, S A R" sort="Webb, S A R" uniqKey="Webb S" first="S A R" last="Webb">S A R. Webb</name></country><country name="Singapour"><noRegion><name sortKey="Lye, D C" sort="Lye, D C" uniqKey="Lye D" first="D C" last="Lye">D C Lye</name></noRegion></country><country name="France"><region name="Centre-Val de Loire"><name sortKey="Bernard, L" sort="Bernard, L" uniqKey="Bernard L" first="L" last="Bernard">L. Bernard</name></region></country><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Doi, Y" sort="Doi, Y" uniqKey="Doi Y" first="Y" last="Doi">Y. Doi</name></region><name sortKey="Fowler, V G" sort="Fowler, V G" uniqKey="Fowler V" first="V G" last="Fowler">V G Fowler</name><name sortKey="Kaye, K S" sort="Kaye, K S" uniqKey="Kaye K" first="K S" last="Kaye">K S Kaye</name><name sortKey="Munoz Price, S" sort="Munoz Price, S" uniqKey="Munoz Price S" first="S" last="Munoz-Price">S. Munoz-Price</name></country><country name="Israël"><noRegion><name sortKey="Leibovici, L" sort="Leibovici, L" uniqKey="Leibovici L" first="L" last="Leibovici">L. Leibovici</name></noRegion><name sortKey="Paul, M" sort="Paul, M" uniqKey="Paul M" first="M" last="Paul">M. Paul</name></country><country name="Afrique du Sud"><noRegion><name sortKey="Lipman, J" sort="Lipman, J" uniqKey="Lipman J" first="J" last="Lipman">J. Lipman</name></noRegion></country><country name="Royaume-Uni"><noRegion><name sortKey="Llewelyn, M J" sort="Llewelyn, M J" uniqKey="Llewelyn M" first="M J" last="Llewelyn">M J Llewelyn</name></noRegion><name sortKey="Thwaites, G" sort="Thwaites, G" uniqKey="Thwaites G" first="G" last="Thwaites">G. Thwaites</name></country><country name="Espagne"><noRegion><name sortKey="Rodriguez Ba O, J" sort="Rodriguez Ba O, J" uniqKey="Rodriguez Ba O J" first="J" last="Rodríguez-Ba O">J. Rodríguez-Ba O</name></noRegion></country><country name="Allemagne"><noRegion><name sortKey="Seifert, H" sort="Seifert, H" uniqKey="Seifert H" first="H" last="Seifert">H. Seifert</name></noRegion></country><country name="Thaïlande"><noRegion><name sortKey="Thamlikitkul, V" sort="Thamlikitkul, V" uniqKey="Thamlikitkul V" first="V" last="Thamlikitkul">V. Thamlikitkul</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Utili, R" sort="Utili, R" uniqKey="Utili R" first="R" last="Utili">R. Utili</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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